Police responded to a fatal collision in Alfredton this morning.
Emergency services were called to Learmonth Street at Arthur Street about 11.50am to reports of a two-car collision.
A woman, who is yet to be formally identified, sadly died at the scene.
Four other people were taken to hospital with non-life-threatening injuries.
The exact circumstances surrounding the incident are yet to be determined and investigations remain ongoing.
Anyone who witnessed the incident, has dashcam footage or any other information that could assist police with their enquiries is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report at www.crimestoppersvic.com.au
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