$35 million for vaccine to end rheumatic heart disease

The eradication of rheumatic heart disease, a deadly and devastating illness largely affecting Indigenous communities, is taking a major step forward, with the Morrison Government investing $35 million in the development of a vaccine to combat the disease.

The funding announced today by Indigenous Health Minister Ken Wyatt AM is being provided from the Medical Research Future Fund (MRFF).
It will allow manufacture and testing of a number of vaccines currently being developed, and fast-tracking and funding of clinical trials in Australia. The aim is to accelerate availability of a vaccine for use in Australia and internationally.
“Today is a game-changing step,” said Minister Wyatt. “Ending RHD is a critical, tangible target to close the gap in Indigenous life expectancy.
“Our Government is building on the work of the Coalition to Advance New Vaccines Against Group A Streptococcus (CANVAS) initiative, by providing $35 million over 3 years to fund the creation of a vaccine that will bring an end, once and for all, to RHD in Australia.
“The trials and development, led by Australia’s leading infectious disease experts and coordinated by the Telethon Kids Institute, will give hope to thousands of First Nations people whose lives and families have been catastrophically affected by this illness.”
Rheumatic Heart Disease (RHD) is a complication of bacterial Streptococcus A infections of the throat and skin. Strep A and RHD are major causes of death around the world, with Strep A killing more than 500,000 people each year.
Australia has one of the highest incidences of rheumatic heart disease in the world. It is the leading cause of cardiovascular inequality between Indigenous and non-Indigenous Australians and is most commonly seen in adolescents and young adults.
Alarmingly, Aboriginal and Torres Strait Islander people are 64 times more likely than non-Indigenous people to develop rheumatic heart disease, and nearly 20 times as likely to die from it.
Every year in Australia, nearly 250 children are diagnosed with acute rheumatic fever at an average age of 10 years. 50 – 150 people, mainly indigenous children or adolescents, die from RHD every year.
“Rheumatic heart disease kills young people and devastates families. This funding will save countless lives in Australia and beyond,” said Health Minister Greg Hunt.
“This initiative will also benefit Australia by ensuring it continues to be the global leader in Strep A and RHD research and public health implementation, and can build on its world-class clinical trial and medical industry.
“Vulnerable communities, in particular Indigenous communities, will get the medicines they need; and Australian industry will have the opportunity to collaborate in developing and distributing the breakthrough vaccine, both here and overseas.”
The End RHD vaccine initiative will be directed by Prof Jonathan Carapetis AM (Director of the Telethon Kids Institute in Perth) and overseen by a Scientific Advisory Board including leading Australian and International experts.
The project will also be informed by an Indigenous Advisory Committee who will ensure that the voices of our First Nations people are heard and acknowledged, and that all components of the work are culturally safe and appropriate.
This latest initiative builds on funding already provided under our Government’s Rheumatic Fever Strategy. This includes $12.8 million to continue support for the existing state-based register and control programs in the Northern Territory, Western Australia, Queensland and South Australia; and new funding of $6 million for focused prevention activities in high-risk communities to prevent the initial incidence of acute rheumatic fever.
Our Government has also provided $165,000 to the
/Public Release.