Police are currently investigating the circumstances surrounding a fatal collision which occurred in Tynong North.
Officers have been told a truck and a 4WD collided on the Princes Highway about 5pm.
The male driver of the 4WD died at the scene while two female passengers suffered life-threatening injuries and were taken to hospital.
The driver is yet to be formally identified at this stage and the exact cause of the crash is yet to be determined.
Anyone who witnessed the incident, or who may have dash cam footage, is asked to call Crime Stoppers on 1800 333 000 or submit a confidential report at www.crimestoppersvic.com.au.
For the current provisional lives lost tally please see https://www.police.vic.gov.au/news