Police are appealing for public assistance to help locate missing woman Mary Hughes.
The 75-year-old was last seen at her residential address in Milne Street Mitcham about 4pm today.
Police and family members hold concerns for her welfare as has she has a medical condition which can cause her to become disoriented.
Investigators have released an image of Mary in the hope someone recognises her and can provide information on her whereabouts.
Mary was last seen wearing stripped t-shirt, blue jeans and white running shoes.
She is known to frequent the Mitcham area.
Anyone who sees Mary or has information on her whereabouts is urged to Forest Hill Police Station on 8847 3600.