Cracking Code Of Life’s Molecular Machinery

Groundbreaking research pioneered by The University of Western Australia is shedding light on the intricate dance between proteins, DNA and RNA – the fundamental building blocks that that carry out cellular processes and underpin all life including plants, humans and bacteria.

Led by Professor Charlie Bond from UWA’s School of Molecular Sciences, a team of scientists has contributed to three studies in the prestigious journal Nucleic Acids Research, showcasing unprecedented three-dimensional models of how protein molecular machines assemble on DNA or RNA.

“We’ve essentially been watching life’s machinery in action at the molecular level,” Professor Bond said.

“By visualising how these complex structures assemble and function, we’re opening doors to entirely new approaches in diagnostics and therapeutic interventions.”

UWA Integrated Crystallisation Facility

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